Thomas Clayton was waived by the Niners, and it looks like there’s a shot that his career could be over:

The worst fears about 49ers running back Thomas Clayton were confirmed Sunday. His season is over with a torn right knee anterior cruciate ligament suffered in Friday night’s exhibition opener against Denver. What’s less clear is if his 49ers career is done, too. The team placed him on the waived/injured list, which means he can be claimed by another organization. But if he clears waivers, as expected, he will revert to the 49ers’ injured reserve list. The reason the 49ers made that procedural move is because they are suddenly down in running backs and it created a roster opening. They used it to sign Bill Rentmeester, a rookie fullback from Wisconsin who was waived Aug. 5 by the San Diego Chargers.